Emerging Infectious Diseases (Mar 2019)

Prospective Whole-Genome Sequencing in Tuberculosis Outbreak Investigation, France, 2017–2018

  • Charlotte Genestet,
  • Caroline Tatai,
  • Jean-Luc Berland,
  • Jean-Baptiste Claude,
  • Emilie Westeel,
  • Elisabeth Hodille,
  • Isabelle Fredenucci,
  • Jean-Philippe Rasigade,
  • Michael Ponsoda,
  • Véronique Jacomo,
  • Anne Vachée,
  • Alice Gaudart,
  • Jean-Louis Gaillard,
  • Anne-Laure Roux,
  • Florence Ader,
  • Karim Tararbit,
  • Garance Terpant,
  • Juliet E. Bryant,
  • Gérard Lina,
  • Oana Dumitrescu

DOI
https://doi.org/10.3201/eid2503.181124
Journal volume & issue
Vol. 25, no. 3
pp. 589 – 592

Abstract

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During June 2017–April 2018, active tuberculosis with Beijing SIT1 isolates was diagnosed in 14 persons living in 4 distant cities in France. Whole-genome sequencing indicated that these patients belonged to a single transmission chain. Whole-genome sequencing–based laboratory investigations enabled prompt tracing of linked cases to improve tuberculosis control.

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