Nature Communications (Nov 2021)

Three-year outcomes of the randomized phase III SEIPLUS trial of extensive intraoperative peritoneal lavage for locally advanced gastric cancer

  • Jing Guo,
  • Aman Xu,
  • Xiaowei Sun,
  • Xuhui Zhao,
  • Yabin Xia,
  • Huamin Rao,
  • Yaming Zhang,
  • Rupeng Zhang,
  • Li Chen,
  • Tao Zhang,
  • Gang Li,
  • Hongtao Xu,
  • Dazhi Xu

DOI
https://doi.org/10.1038/s41467-021-26778-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 7

Abstract

Read online

Extensive intraoperative peritoneal lavage (EIPL) has been proposed as an approach to reduce peritoneal metastasis in patients with locally advanced gastric cancer undergoing gastrectomy. Here the authors report the results of the multicentric phase III SEIPLUS trial, showing that EIPL does not improve 3-year survival rate in patients with advanced gastric cancer.