Mediators of Inflammation (Jan 2004)
Mast cells are responsible for the lack of anti-inflammatory effects of morphine in CBA mice
Abstract
BACKGROUND and aim: Morphine co-injection has anti-inflammatory effects on zymosan-induced peritonitis in several strains of mice except that of CBA. As peritoneal mast cells (pMCs) are much more numerous in CBA mice than in SWISS mice, the role of pMCs in morphine-modulated zymosan peritonitis is compared in CBA and SWISS males.
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