Fertility & Reproduction (Jun 2023)
Recurrent Implantation Failure Associated to Morular Endometrial Metaplasia, and Hysteroscopic Management
Abstract
We report the first documented case of recurrent implantation failure (RIF) related to morular endometrial metaplasia. A 35-year-old woman with RIF was diagnosed with endometrial morular metaplasia and treated with hysteroscopically guided excision allowing a live birth after the transfer of a single IVF embryo. Subtle endometrial changes, such as endometritis or bone metaplasia, have long been known to impair the success of embryo implantation, but this observation reports the first case of squamous morular endometrial metaplasia to be diagnosed and treated conservatively before a successful single embryo transfer.
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