Frontiers in Immunology (Feb 2021)
Case Report: Early Transplant Rejection of a Methanol-Intoxicated Donor Heart in a Young Female Patient. A Diagnostic Approach With CMR, Cardiac Biopsy, and Genetic Risk Assessment
- Lukas Stoiber,
- Lukas Stoiber,
- Felix Schoenrath,
- Felix Schoenrath,
- Christoph Knosalla,
- Christoph Knosalla,
- Hendrik Milting,
- Karin Klingel,
- Carsten Tschöpe,
- Carsten Tschöpe,
- Radu Tanacli,
- Rolf Gebker,
- Alexander Berger,
- Burkert Pieske,
- Burkert Pieske,
- Burkert Pieske,
- Sebastian Kelle,
- Sebastian Kelle,
- Sebastian Kelle
Affiliations
- Lukas Stoiber
- Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Berlin, Germany
- Lukas Stoiber
- Department of Internal Medicine and Cardiology, German Heart Center Berlin, Berlin, Germany
- Felix Schoenrath
- Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Berlin, Germany
- Felix Schoenrath
- DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
- Christoph Knosalla
- Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Berlin, Germany
- Christoph Knosalla
- DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
- Hendrik Milting
- Erich and Hanna Klessmann Institute for Cardiovascular Research & Development (EHKI), Heart and Diabetes Center North Rine-Westphalia (NRW), University Hospital of the Ruhr-University Bochum, Bad Oeynhausen, Germany
- Karin Klingel
- Cardiopathology, Institute for Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany
- Carsten Tschöpe
- DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
- Carsten Tschöpe
- Department of Internal Medicine and Cardiology, Charité University Medicine Berlin, Berlin, Germany
- Radu Tanacli
- Department of Internal Medicine and Cardiology, German Heart Center Berlin, Berlin, Germany
- Rolf Gebker
- Department of Internal Medicine and Cardiology, German Heart Center Berlin, Berlin, Germany
- Alexander Berger
- Department of Internal Medicine and Cardiology, German Heart Center Berlin, Berlin, Germany
- Burkert Pieske
- Department of Internal Medicine and Cardiology, German Heart Center Berlin, Berlin, Germany
- Burkert Pieske
- DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
- Burkert Pieske
- Department of Internal Medicine and Cardiology, Charité University Medicine Berlin, Berlin, Germany
- Sebastian Kelle
- Department of Internal Medicine and Cardiology, German Heart Center Berlin, Berlin, Germany
- Sebastian Kelle
- DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
- Sebastian Kelle
- Department of Internal Medicine and Cardiology, Charité University Medicine Berlin, Berlin, Germany
- DOI
- https://doi.org/10.3389/fimmu.2020.575635
- Journal volume & issue
-
Vol. 11
Abstract
This case report describes the contributions of multimodality imaging, cardiac biopsy, and genetic sequencing to the diagnosis and management of heart transplant rejection in a 23-year old patient with dilated cardiomyopathy.
Keywords
- cardiac magnetic resonance imaging (CMR)
- heart transplantation
- gene sequence
- cardiomyopathy
- mapping - magnetic resonance imaging
