Triamcinolone acetonide acetate

Abstract

In the crystal structure of the title compound [systematic name: 2-(4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-7,9-dioxapentaleno[2,1-a]phenanthren-6b-yl)-2-oxoethyl acetate], C26H33FO7, the molecules are connected by intermolecular O—H...O hydrogen bonds into an infinite supramolecular chain along the b axis. The molecular framework consists of five condensed rings, including three six-membered rings and two five-membered rings. The cyclohexa-2,5-dienone ring is nearly planar [maximum deviation = 0.013 (3) Å], while the cyclohexane rings adopt chair conformations. The two five-membered rings, viz. cyclopentane and 1,3-dioxolane, display envelope conformations.