<i>Hypericum</i> Essential Oils—Composition and Bioactivities: An Update (2012–2022)
Maria-Eleni Grafakou,
Christina Barda,
George Albert Karikas,
Helen Skaltsa
Affiliations
Maria-Eleni Grafakou
Department of Pharmacognosy & Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National & Kapodistrian University of Athens, 15771 Athens, Greece
Christina Barda
Department of Pharmacognosy & Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National & Kapodistrian University of Athens, 15771 Athens, Greece
George Albert Karikas
Department of Biomedical Sciences, University of West Attica, 12243 Athens, Greece
Helen Skaltsa
Department of Pharmacognosy & Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National & Kapodistrian University of Athens, 15771 Athens, Greece
Hypericum genus, considered to comprise over 500 species that exhibit cosmopolitan distribution, has attracted human interest since ancient times. The present review aims to provide and summarize the recent literature (2012–2022) on the essential oils of the title genus. Research articles were collected from various scientific databases such as PubMed, ScienceDirect, Reaxys, and Google Scholar. Scientific reports related to the chemical composition, as well as the in vitro and in vivo pharmacological activities, are presented, also including a brief outlook of the potential relationship between traditional uses and Hypericum essential oils bioactivity.
