mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies

Even H. Rustad; Ferran Nadeu; Nicos Angelopoulos; Bachisio Ziccheddu; Niccolò Bolli; Xose S. Puente; Elias Campo; Ola Landgren; Francesco Maura

doi:10.1038/s42003-021-01938-0

Communications Biology (Mar 2021)

mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies

Even H. Rustad,
Ferran Nadeu,
Nicos Angelopoulos,
Bachisio Ziccheddu,
Niccolò Bolli,
Xose S. Puente,
Elias Campo,
Ola Landgren,
Francesco Maura

Affiliations

Even H. Rustad: Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center
Ferran Nadeu: Patologia Molecular de Neoplàsies Limfoides, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
Nicos Angelopoulos: School of Medicine, Systems Immunity Research Institute, Cardiff University
Bachisio Ziccheddu: Department of Molecular Biotechnologies and Health Sciences, University of Turin
Niccolò Bolli: Department of Oncology and Hemato-Oncology, University of Milan
Xose S. Puente: Departamento de Bioquimica y Biologia Molecular, Instituto Universitario de Oncologia (IUOPA), Universidad de Oviedo
Elias Campo: Patologia Molecular de Neoplàsies Limfoides, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
Ola Landgren: Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center
Francesco Maura: Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center

DOI: https://doi.org/10.1038/s42003-021-01938-0
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 12

Abstract

Read online

Rustad et al. present a software package for the R statistical environment for the accurately quantify of somatic mutational signatures in hematological malignancies

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal