Effects of Exercise on Memory Retrieval in Passive Avoidance Learning in Young Male Wistar Rats

Abstract

Background and Objectives Exercise seems to be a simple and widely practiced behavior that activates molecular and cellular signaling cascades involved in various central nervous system processes. There has been more attention to the effects of exercise on nervous system and memory during recent years. So, we decided to examine the effects of treadmill exercise on memory consolidation and retrieval in young rats by passive avoidance learning. Methods In this study fifty male Wistar rats (3-4 months old) were randomly divided into five groups (n=10). Those in the control group were trained in passive avoidance box and tested 10 min, 24 hrs, 10 days and 3 months later. Two groups exercised in treadmill one hour at 17 m/min for 10 days and 3 months respectively and then were trained in passive avoidance box and tested 10 min and 24 hrs later. Data were analyzed using T and paired T tests. The other two groups for research effects of exercise in memory retrieval first were trained and tested 10 days and 24 hrs later and then exercised in treadmill like the other two groups; the latter groups were tested after exercise. Results The obtained results showed that short–term (10 days) and long – term(3 months) exercise before training had significant (P<0.05) effects on memory consolidation in passive avoidance learning, but no difference was observed in latency time in passive avoidance between short–term (10 days) and long–term(3 months) exercise groups after training with before exercise. Conclusion Our results showed that physical activity produced a significant enhancement on learning and memory consolidation but there were no significant effects on memory retrieval.

Keywords

• exercise
• mental recall
• exercise test
• retention (psychology)
• rat
• avoidance learning