Predisposed genomic instability in pre-treatment bone marrow evolves to therapy-related myeloid neoplasms in malignant lymphoma

• Seiichiro Katagiri,
• Hideki Makishima,
• Kenko Azuma,
• Yasuhito Nannya,
• Yuu Saitoh,
• Seiichiro Yoshizawa,
• Daigo Akahane,
• Hiroaki Fujimoto,
• Yoshikazu Ito,
• Ravi Velaga,
• Tomohiro Umezu,
• Junko H. Ohyashiki,
• Seishi Ogawa,
• Kazuma Ohyashiki

Affiliations

Seiichiro Katagiri

Department of Hematology, Tokyo Medical University, Tokyo, Japan

Hideki Makishima

Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan

Kenko Azuma

Department of Molecular Oncology, Institute of Medical Science, Tokyo Medical University, Tokyo, Japan;Current address: Tokyo Women's Medical University Institute for Integrated Medical Sciences (TIIMS), Tokyo, Japan

Yasuhito Nannya

Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan

Yuu Saitoh

Department of Hematology, Tokyo Medical University, Tokyo, Japan

Seiichiro Yoshizawa

Department of Hematology, Tokyo Medical University, Tokyo, Japan

Daigo Akahane

Department of Hematology, Tokyo Medical University, Tokyo, Japan

Hiroaki Fujimoto

Department of Hematology, Tokyo Medical University, Tokyo, Japan

Yoshikazu Ito

Department of Hematology, Tokyo Medical University, Tokyo, Japan

Ravi Velaga

Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan

Tomohiro Umezu

Department of Hematology, Tokyo Medical University, Tokyo, Japan;Department of Advanced Cellular Therapy, Tokyo Medical University, Tokyo, Japan

Junko H. Ohyashiki

Department of Advanced Cellular Therapy, Tokyo Medical University, Tokyo, Japan

Seishi Ogawa

Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan;Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan;Department of Medicine, Centre for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden

Kazuma Ohyashiki

Department of Hematology, Tokyo Medical University, Tokyo, Japan;Department of Advanced Cellular Therapy, Tokyo Medical University, Tokyo, Japan