A protocol for the use of cloud-based quantum computers for logical network analysis of biological systems

Abstract

Summary: Boolean networks are commonly used in systems biology to dynamically model gene regulatory interactions. Here, we present a protocol for implementing Boolean network dynamics as quantum circuits. We describe steps for accessing cloud-based quantum processing units offered by IBM and IonQ and downloading and parsing logic for gene regulatory networks. We then detail procedures for performing simulations of quantum circuits on local devices and visualizing measurement results.For complete details on the use and execution of this protocol, please refer to Weidner et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.

Keywords

• Systems biology
• Computer sciences