P20 Achievement of objectives in Adult patients with type 1 Diabetes: Estimated Glucose Disposition Rate as a Clinical Marker

Abstract

Introduction and Objective: The Clinical Practice Guidelines in diabetes establish precise clinical objectives on the good management of the disease, but little is known about adequate compliance in our environment. Being overweight and sedentary have generated stigmas of metabolic syndrome in the population with DM1. We evaluated compliance with 5 of these criteria: HbA1c <7%, LDL≤100mg / dl, Physical Activity ≥3 times/week, systolic BP <140mmHg and no smoking and its association with insulin resistance determined by the estimated Glucose Disposition Rate (eGDR). Material and methods: In 415 DM1 ≥18 years, 52% women, age 34.8 ± 13.9 years, HbA1c, LDLC, weekly frequency of structured physical activity, systolic BP and current smoking were evaluated. The degree of association with gender, age, age of diabetes, level of education, medical coverage, BMI, and insulin sensitivity measured through eGDR was determined. Qualitative variables were analyzed by chi square test and quantitative variables by ANOVA I test corrected by Tukey's test for multiple comparisons. A value of p <0.05 was considered statistically significant. A 95% confidence interval was used in all cases.

Keywords

• diabetes tipo 1
• disposición de glucosa
• marcador clínico