Frontiers in Pediatrics (Dec 2019)

Lupus Nephritis With Mild Asymptomatic Hypercalcemia in Children: A Case Report and Literature Review

  • Lingling Xu,
  • Jun Zhang,
  • Ronghui Pu,
  • Zhihui Yue,
  • Ying Mo,
  • Xiaoyun Jiang

DOI
https://doi.org/10.3389/fped.2019.00507
Journal volume & issue
Vol. 7

Abstract

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Lupus nephritis (LN) in Children is caused by Kidney involvement in systemic lupus erythematosus (SLE). SLE is a chronic, multi-systemic, paroxysmal autoimmune disease with a wide spectrum of autoantibodies. Hypercalcemia is a common manifestation of primary hyperparathyroidism and other malignant tumors. LN or SLE with hypercalcemia is rare. We report a case of LN with hypercalcemia and review the literature. It suggests that the pathogenesis of SLE complicated with hypercalcemia complicates the response of drug therapy.

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