Further Investigation of Synaptic Vesicle Protein 2A (SV2A) Ligands Designed for Positron Emission Tomography and Single-Photon Emission Computed Tomography Imaging: Synthesis and Structure–Activity Relationship of Substituted Pyridinylmethyl-4-(3,5-difluorophenyl)pyrrolidin-2-ones
Richard Pracitto,
Kyle C. Wilcox,
Marcel Lindemann,
Jie Tong,
Chao Zheng,
Songye Li,
Sjoerd J. Finnema,
Yiyun Huang,
Zhengxin Cai
Affiliations
Richard Pracitto
PET Center, Yale University School of Medicine, New Haven, Connecticut, United States
Kyle C. Wilcox
Translational Imaging Neuroscience, AbbVie, North Chicago, Illinois, United States
Marcel Lindemann
PET Center, Yale University School of Medicine, New Haven, Connecticut, United States
Jie Tong
PET Center, Yale University School of Medicine, New Haven, Connecticut, United States
Chao Zheng
PET Center, Yale University School of Medicine, New Haven, Connecticut, United States
Songye Li
PET Center, Yale University School of Medicine, New Haven, Connecticut, United States
Sjoerd J. Finnema
PET Center, Yale University School of Medicine, New Haven, Connecticut, United States
Yiyun Huang
PET Center, Yale University School of Medicine, New Haven, Connecticut, United States
Zhengxin Cai
PET Center, Yale University School of Medicine, New Haven, Connecticut, United States