ACS Omega (Apr 2020)
Lead Identification of 8‑(Methylamino)-2-oxo-1,2-dihydroquinoline Derivatives as DNA Gyrase Inhibitors: Hit-to-Lead Generation Involving Thermodynamic Evaluation
- Fumihito Ushiyama,
- Hideaki Amada,
- Tomoki Takeuchi,
- Nozomi Tanaka-Yamamoto,
- Harumi Kanazawa,
- Koichiro Nakano,
- Masashi Mima,
- Aiko Masuko,
- Iichiro Takata,
- Kosuke Hitaka,
- Kunihiko Iwamoto,
- Hiroyuki Sugiyama,
- Norikazu Ohtake
Affiliations
- Fumihito Ushiyama
- Chemistry Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Hideaki Amada
- Chemistry Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Tomoki Takeuchi
- Chemistry Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Nozomi Tanaka-Yamamoto
- Chemistry Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Harumi Kanazawa
- Chemistry Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Koichiro Nakano
- Pharmacology Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Masashi Mima
- Pharmacology Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Aiko Masuko
- Pharmacology Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Iichiro Takata
- Pharmacology Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Kosuke Hitaka
- Pharmacology Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Kunihiko Iwamoto
- Pharmacology Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Hiroyuki Sugiyama
- Pharmacology Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- Norikazu Ohtake
- Chemistry Laboratories, Taisho Pharmaceutical Company Ltd., Saitama, Saitama, Japan
- DOI
- https://doi.org/10.1021/acsomega.0c00865
- Journal volume & issue
-
Vol. 5,
no. 17
pp. 10145 – 10159
Abstract
No abstracts available.
