Single Daily Dosing of Gentamicin: Pharmacokinetic Comparison of Two Dosing Methodologies for Postpartum Endometritis

C.  Liu; B.  Abate; M.  Reyes; B.  Gonik

doi:10.1155/S1064744999000216

Infectious Diseases in Obstetrics and Gynecology (Jan 1999)

Single Daily Dosing of Gentamicin: Pharmacokinetic Comparison of Two Dosing Methodologies for Postpartum Endometritis

C. Liu,
B. Abate,
M. Reyes,
B. Gonik

Affiliations

C. Liu: Department of Pharmacy, Detroit Medical Center and Wayne State University, Detroit, MI, USA
B. Abate: Department of Pharmacy, Detroit Medical Center and Wayne State University, Detroit, MI, USA
M. Reyes: Department of Medicine (Infectious Diseases), Detroit Medical Center and Wayne State University, Detroit, MI, USA
B. Gonik: Department of Obstetrics and Gynecology, Detroit Medical Center and Wayne State University, Detroit, MI, USA

DOI: https://doi.org/10.1155/S1064744999000216
Journal volume & issue: Vol. 7, no. 3
pp. 133 – 137

Abstract

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Objective: We compared the pharmacokinetics of two methods for dosing gentamicin for the treatment of postpartum endometritis with the goal of achieving adequate peak serum concentrations (>12 mg/L) and prolonged trough levels below 2 mg/L.

Published in Infectious Diseases in Obstetrics and Gynecology

ISSN: 1064-7449 (Print); 1098-0997 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Gynecology and obstetrics; Medicine: Internal medicine: Infectious and parasitic diseases
Website: https://onlinelibrary.wiley.com/journal/7281

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