Dnase1 Family in Autoimmunity

Minal Engavale; Jon McCord; Britney Mapp; Nadine Nzimulinda; Elisabeth Bengtson; R. Bryan Sutton; Peter A. Keyel

doi:10.3390/encyclopedia1030044

Encyclopedia (Jul 2021)

Dnase1 Family in Autoimmunity

Minal Engavale,
Jon McCord,
Britney Mapp,
Nadine Nzimulinda,
Elisabeth Bengtson,
R. Bryan Sutton,
Peter A. Keyel

Affiliations

Minal Engavale: Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA
Jon McCord: Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Science Center, Lubbock, TX 79430, USA
Britney Mapp: Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA
Nadine Nzimulinda: Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA
Elisabeth Bengtson: Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA
R. Bryan Sutton: Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Science Center, Lubbock, TX 79430, USA
Peter A. Keyel: Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA

DOI: https://doi.org/10.3390/encyclopedia1030044
Journal volume & issue: Vol. 1, no. 3
pp. 527 – 541

Abstract

Read online

The deoxyribonuclease 1 (Dnase1) family is a key family of endonucleases that degrades DNA. Loss of Dnase1 family function causes several diseases where the host’s immune system targets the host, such as systemic lupus erythematosus, hypocomplementemic urticarial vasculitis syndrome.

Published in Encyclopedia

ISSN: 2673-8392 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science
Website: https://www.mdpi.com/journal/encyclopedia

About the journal

Abstract

Keywords