Type 1 neurofibromatosis with periodontal manifestations

Abstract

Neurofibromatosis type 1 (NF1) also known as von Recklinghausen's disease is an autosomal dominant disease transmitted with a high degree of penetrance. The disease is expressed in different forms. NF1 accounts for almost 90% of the cases although nine types have been described to date. We report one such case of a 36-year-old female who presented with multiple nodules on the body. He was diagnosed to have NF1, having satisfied the diagnostic criteria for the same. Oral manifestations can be found in almost 72% of NF1 patients. This case report highlights the clinical features and diagnostic criteria of NF1, the prevalence and the significance of intraoral neurofibromas and the need for the dental practitioner to be aware of this condition.

Keywords

• Neurofibromas
• neurofibromatosis
• Von Recklinghausen's disease