Hematological parameters as a risk for developing metabolic syndrome in the adult population of Kashmir (India)

Abstract

Background and Aim: Various studies have reported an association of hematological parameters such as red blood cell (RBC), hemoglobin (Hb), hematocrit (HCT), white blood cell (WBC), and platelets with metabolic syndrome (MS) in many parts of the world. However, the association of these parameters with MS in terms of gender has not been elucidated particularly in the ethnic population of northern India. Thus, the study aimed at exploring the association of these hematological parameters with MS stratified by gender in the Kashmiri region of India. Materials and Methods: A total of 400 people were enrolled in this study consisting of 204 men and 196 women. MS was diagnosed by the International Diabetes Federation criteria. For statistical analysis, SPSS software and Pearson Partial coefficient analysis were used. Results: The prevalence of MS was (50.6% vs. 20.6%) in women and men. WBC and platelets were significantly increased in men with MS (P ≤ 0.05). RBC, Hb, HCT, and platelets were significantly increased in women with MS (P ≤ 0.05). Furthermore, in men, WBC and platelet count increased with the increasing number of MS components. Whereas, in women RBC, Hb, HCT, and platelet count increased with the increasing number of MS components (0, 1, 2, and ≥3). Conclusion: MS was more widespread in women than men than women. The association of hematological parameters differed between the genders. WBC and platelets were found to be the risk factors in men and RBC, Hb, HCT, and platelets were found to be the risk factors in women for MS. These hematological parameters could be used for assessing the risk of MS on the basis of gender.

Keywords

• hematological parameters
• insulin resistance
• kashmir
• metabolic syndrome