Frontiers in Cardiovascular Medicine (Oct 2024)

P-wave terminal force in lead V1 is associated with recurrence after catheter ablation in patients with paroxysmal atrial fibrillation and normal left atrial size

  • Zhao Wang,
  • Zhao Wang,
  • Zhao Wang,
  • Binhao Wang,
  • Binhao Wang,
  • Yiheng Yang,
  • Xiaolei Yang,
  • Ying Che,
  • Yunlong Xia

DOI
https://doi.org/10.3389/fcvm.2024.1467585
Journal volume & issue
Vol. 11

Abstract

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BackgroundA previous investigation reported that an abnormal P-wave terminal force in lead V1 (PTFV1) is a marker for electrical remodeling of the left atrium (LA). We aimed to assess the relationship of PTFV1 with LA tachyarrhythmia (LATA) recurrence after radiofrequency catheter ablation (RFCA) in patients with paroxysmal atrial fibrillation (PAF) and normal LA size.MethodsPatients with PAF and normal LA size (LA volume index < 34 ml/m2) who underwent RFCA were consecutively included between January 2018 and December 2020 and divided into two groups based on the presence (recurrence group) or absence (nonrecurrence group) of LATA recurrence. PTFV1 was measured according to preprocedural electrocardiography. The association between PTFV1 and the recurrence of LATA was investigated.ResultsA total of 385 patients were included. After a median follow-up period of 745 (467, 977) days, 109 (28.3%) patients experienced LATA recurrence. PTFV1 was greater in the recurrence group. Multivariate Cox regression analysis demonstrated that the hazard ratio and 95% confidence interval for PTFV1 per 1,000 μV*ms increase and PTFV1 > 4,000 μV*ms were 1.22 (1.13–1.32, p < 0.001) and 2.32 (1.54–3.48, p < 0.001), respectively.ConclusionPTFV1 is an independent predictor for LATA recurrence after RFCA in patients with PAF and normal LA size.

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