Advancements in nanobiosensor technologies for in-vitro diagnostics to point of care testing

Abstract

Recently, the importance of rapid testing nanosensor technologies for in-vitro diagnostics (IVD) and point-of-care testing (POCT) is being increasingly recognized. Owing to their high sensitivity and rapidity, nanosensor-based diagnostic devices are evolving into self-diagnostic tools that enable real-time in-situ analyses. These advances have become the focus of the public health control system, not only to prevent the spread of infectious diseases but also to enable the early detection of critical diseases through continuous health monitoring technologies. Current research on rapid diagnostic nanosensor technologies has focused on improving accuracy, sensitivity, rapid test systems, cost-effectiveness, and accessibility. In this review, we discuss the development of self-testing IVD technologies based on rapid diagnostic nanosensor platforms. The convergence of nanosensors and advanced materials can provide faster, more accurate, and more accessible IVD-based POCT solutions, representing an important advancement in healthcare. Here, we present nanosensor technologies for diagnosing biomarkers in in-vitro samples and improving diagnostic efficiency. Nanosensor-based self-diagnostic devices have the potential to be extended to personalized healthcare platforms, enabling the continuous monitoring of infectious diseases, cancer, and other serious issues. This review highlights the importance of research in this field to improve diagnostic efficiency.

Keywords

• Nanosensors
• In-vitro diagnostics
• Point of care testing
• Rapid test
• Healthcare devices