Nature Communications (Jun 2022)
Innate immune responses against the fungal pathogen Candida auris
- Yuanyuan Wang,
- Yun Zou,
- Xiaoqing Chen,
- Hao Li,
- Zhe Yin,
- Baocai Zhang,
- Yongbin Xu,
- Yiquan Zhang,
- Rulin Zhang,
- Xinhua Huang,
- Wenhui Yang,
- Chaoyue Xu,
- Tong Jiang,
- Qinyu Tang,
- Zili Zhou,
- Ying Ji,
- Yingqi Liu,
- Lingfei Hu,
- Jia Zhou,
- Yao Zhou,
- Jingjun Zhao,
- Ningning Liu,
- Guanghua Huang,
- Haishuang Chang,
- Wenxia Fang,
- Changbin Chen,
- Dongsheng Zhou
Affiliations
- Yuanyuan Wang
- The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Yun Zou
- The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Xiaoqing Chen
- The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Hao Li
- Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- Zhe Yin
- State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology
- Baocai Zhang
- State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
- Yongbin Xu
- Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine
- Yiquan Zhang
- Wuxi School of Medicine, Jiangnan University
- Rulin Zhang
- Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- Xinhua Huang
- The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Wenhui Yang
- State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology
- Chaoyue Xu
- The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Tong Jiang
- The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Qinyu Tang
- Department of Dermatology, Tongji Hospital, Tongji University School of Medicine
- Zili Zhou
- The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Ying Ji
- The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Yingqi Liu
- School of Basic Medicine, Gannan Medical University
- Lingfei Hu
- State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology
- Jia Zhou
- Center for Single-Cell Omics, School of Public Health, Shanghai Jiaotong University School of Medicine
- Yao Zhou
- National Engineering Research Center for Non-Food Biorefinery, Guangxi Academy of Sciences
- Jingjun Zhao
- Department of Dermatology, Tongji Hospital, Tongji University School of Medicine
- Ningning Liu
- Center for Single-Cell Omics, School of Public Health, Shanghai Jiaotong University School of Medicine
- Guanghua Huang
- Department of Infectious Disease, Huashan Hospital and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University
- Haishuang Chang
- Shanghai Institute of Precision Medicine, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine
- Wenxia Fang
- National Engineering Research Center for Non-Food Biorefinery, Guangxi Academy of Sciences
- Changbin Chen
- The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences
- Dongsheng Zhou
- State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology
- DOI
- https://doi.org/10.1038/s41467-022-31201-x
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 20
Abstract
Candida auris is a multidrug-resistant human fungal pathogen responsible for nosocomial outbreaks worldwide. Here, the authors identify differential innate immune responses induced by C. auris and Candida albicans in vitro and in vivo, which correlate with structural features of the cell wall.
