3-(2-Aminoethyl)-2-(4-chloroanilino)quinazolin-4(3H)-one methanol 0.75-solvate

Abstract

In the asymmetric unit of the title compound, C16H15ClN4O·0.75CH3OH, there are two independent quinazolin-4(3H)-one molecules and one and a half methanol molecules. One of the methanol molecules is disordered over two positions with equal occupancies. The dihedral angles between the quinazoline ring system and the chlorobenzene ring in the two quinazolin-4(3H)-one molecules are essentially the same, at 39.83 (1) and 39.84 (1)°. Intramolecular N—H...N and O—H...O, and intermolecular N—H...O and N—H...N hydrogen bonds are observed. In addition, π–π stacking interactions, with centroid-to-centroid distances of 3.654 (1), 3.766 (1) and 3.767 (1) Å, and weak C—H...π interactions, are observed.