Research of the effect of cerebral microbleeds on spontaneous cerebral hemorrhage

Abstract

Cerebral microbleeds (CMBs) is one of the most important neuroimaging markers of cerebral small vessel disease (cSVD). It has been validated that the number and spatial distribution of CMBs are closely related to the risk of first ⁃ ever and recurrence of spontaneous cerebral hemorrhage.CMBs account ≥ 5 and strictly limited in brain lobar are risk factors for increased incidence of spontaneous cerebral hemorrhage. In addition, CMBs could also serve as a potential predictive factor for the risk of rupture of cerebral aneurysms and the occurrence of Moyamoya disease ⁃ related spontaneous cerebral hemorrhage. Thus, CMBs would be very important for stratification of cerebral hemorrhage patients in clinical studies, and could provide complementary information for neurosurgeons to make surgical decisions.

Keywords

• Cerebral hemorrhage; Review