Resveratrol Trimers from Seed Cake of Paeonia rockii
Pu Liu,
Yiran Wang,
Jiayu Gao,
Zongyuan Lu,
Weiping Yin,
Ruixue Deng
Affiliations
Pu Liu
Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China
Yiran Wang
Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China
Jiayu Gao
Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China
Zongyuan Lu
Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China
Weiping Yin
Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China
Ruixue Deng
Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China
In the course of screening natural products for antibacterial activities, a total acetone extract of the seed cake of Paeonia rockii showed significant effects against bacterial strains. Bioactivity-guided fractionation of the EtOAc-soluble fraction of the total acetone extract resulted in the isolation and identification of five resveratrol trimers, including rockiiol C (1), gnetin H (2), suffruticosol A (3), suffruticosol B (4) and suffruticosol C (5). The relative configuration of these compounds was elucidated mainly by comprehensive 1D and 2D-NMR experiments. Compound 1 was a new compound. All isolated compounds exhibited strong antibacterial activities against Gram-positive bacteria.
