Brazilian Journal of Pharmaceutical Sciences (Sep 2015)

Cardiovascular risk rate in hypertensive patients attended in primary health care units: the influence of pharmaceutical care

  • Paulo Yuri Milen Firmino,
  • Tainá Osterno Vasconcelos,
  • Caroline Carneiro Ferreira,
  • Larissa Mendonça Moreira,
  • Nirla Rodrigues Romero,
  • Lilian Araújo Dias,
  • Maria Goretti Rodrigues de Queiroz,
  • Marcos Venícios de Oliveira Lopes,
  • Marta Maria de França Fonteles

DOI
https://doi.org/10.1590/S1984-82502015000300013
Journal volume & issue
Vol. 51, no. 3
pp. 617 – 627

Abstract

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Cardiovascular complications are relevant due to their frequency and severity on the hypertension scenario. Studies refer Pharmaceutical Care (PC) as capable of decreasing cardiovascular risk rate (%CVR) on hypertensive patients. This study aimed to investigate, through a randomized clinical assay, the influence of PC service on the %CVR of hypertensive patients assisted in a health primary care unit from Fortaleza-Ceará. Two study groups were formed: i. Intervention Group (IG), which received orientation about taking medicines, actions aiming to prevent/solve medicine interactions and adverse effects and non-pharmacological interventions for 9 months and, ii. Control Group (CG), which received traditional assistance of the unit and was monitored during the same period. It was observed a statistically significant reduction on %CVR (10.76 to 7.86; p=0.04) and systolic blood pressure levels (SBP) (137.69 to 131.54; p<0.01) in the IG, while, in the CG, there was no significant alteration. 151 Drug Related Problem (DRP) were identified and it was realized 124 pharmaceutical interventions, with 89.2% of them resulting on solution/prevention of the problem. Our findings indicated that the inclusion of the PC service in the hypertensive health assistance was more effective at the %CVR and the SBP reduction in comparison to the traditional assistance offered.

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