Emerging Microbes and Infections (Dec 2023)

Place of magistral preparations to continue the treatment if the drug is commercially stopped worldwide? A case report of a 10-year-old child with subacute sclerosing panencephalitis (SSPE) requiring inosiplex

  • Renan Le Cras,
  • Roseline Mazet,
  • Fanny Dubois-Teklali,
  • Cécile Sabourdy,
  • Sébastien Chanoine,
  • Audrey Lehmann,
  • Agathe Morin,
  • Julien Leenhardt,
  • Marjorie Durand,
  • Marie-Dominique Desruet,
  • Pierrick Bedouch

DOI
https://doi.org/10.1080/22221751.2022.2148563
Journal volume & issue
Vol. 12, no. 1

Abstract

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ABSTRACTSubacute sclerosing panencephalitis (SSPE) is a late-onset and fatal viral disease caused by persistent infection of the central nervous system by measles virus (MeV). We present the case of a 10-year-old child from South Asia affected by SSPE, stabilized with a combination of intrathecal interferon-α2b (INF-α2b) injections and oral inosiplex and how we continued the treatment when inosiplex was commercially stopped worldwide.

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