Early SARS-CoV-2 dynamics and immune responses in unvaccinated participants of an intensely sampled longitudinal surveillance study

Manjula Gunawardana; Simon Webster; Sofia Rivera; John M. Cortez; Jessica Breslin; Cristian Pinales; Christopher Buser; F. Javier Ibarrondo; Otto O. Yang; Michael Bobardt; Philippe A. Gallay; Amy P. Adler; Christina M. Ramirez; Peter A. Anton; Marc M. Baum

doi:10.1038/s43856-022-00195-4

Communications Medicine (Oct 2022)

Early SARS-CoV-2 dynamics and immune responses in unvaccinated participants of an intensely sampled longitudinal surveillance study

Manjula Gunawardana,
Simon Webster,
Sofia Rivera,
John M. Cortez,
Jessica Breslin,
Cristian Pinales,
Christopher Buser,
F. Javier Ibarrondo,
Otto O. Yang,
Michael Bobardt,
Philippe A. Gallay,
Amy P. Adler,
Christina M. Ramirez,
Peter A. Anton,
Marc M. Baum

Affiliations

Manjula Gunawardana: Department of Chemistry, Oak Crest Institute of Science
Simon Webster: Department of Chemistry, Oak Crest Institute of Science
Sofia Rivera: Department of Chemistry, Oak Crest Institute of Science
John M. Cortez: Department of Chemistry, Oak Crest Institute of Science
Jessica Breslin: Department of Chemistry, Oak Crest Institute of Science
Cristian Pinales: Department of Chemistry, Oak Crest Institute of Science
Christopher Buser: Department of Chemistry, Oak Crest Institute of Science
F. Javier Ibarrondo: University of California, Los Angeles (UCLA), Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine at UCLA
Otto O. Yang: University of California, Los Angeles (UCLA), Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine at UCLA
Michael Bobardt: Department of Immunology and Microbiology, The Scripps Research Institute
Philippe A. Gallay: Department of Immunology and Microbiology, The Scripps Research Institute
Amy P. Adler: Jumpstart Research Consulting, LLC
Christina M. Ramirez: University of California, Los Angeles (UCLA), Department of Biostatistics, Fielding School of Public Health, UCLA
Peter A. Anton: Department of Chemistry, Oak Crest Institute of Science
Marc M. Baum: Department of Chemistry, Oak Crest Institute of Science

DOI: https://doi.org/10.1038/s43856-022-00195-4
Journal volume & issue: Vol. 2, no. 1
pp. 1 – 15

Abstract

Read online

Gunawardana et al. monitor the viral load, inflammatory biomarkers and antibody response long-term in people who developed COVID-19. Early viral replication is rapid, providing a narrow window between exposure and viral shedding.

Published in Communications Medicine

ISSN: 2730-664X (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Medicine
Website: https://www.nature.com/commsmed/

About the journal