Vaccines (Mar 2024)

Estimating the Impact of Vaccination Campaigns on Measles Transmission in Somalia

  • Niket Thakkar,
  • Ali Haji Adam Abubakar,
  • Mukhtar Shube,
  • Mustafe Awil Jama,
  • Mohamed Derow,
  • Philipp Lambach,
  • Hossam Ashmony,
  • Muhammad Farid,
  • So Yoon Sim,
  • Patrick O’Connor,
  • Anna Minta,
  • Anindya Sekhar Bose,
  • Patience Musanhu,
  • Quamrul Hasan,
  • Naor Bar-Zeev,
  • Sk Md Mamunur Rahman Malik

DOI
https://doi.org/10.3390/vaccines12030314
Journal volume & issue
Vol. 12, no. 3
p. 314

Abstract

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Somalia is a complex and fragile setting with a demonstrated potential for disruptive, high-burden measles outbreaks. In response, since 2018, Somalian authorities have partnered with UNICEF and the WHO to implement measles vaccination campaigns across the country. In this paper, we create a Somalia-specific model of measles transmission based on a comprehensive epidemiological dataset including case-based surveillance, vaccine registries, and serological surveys. We use this model to assess the impact of these campaign interventions on Somalian’s measles susceptibility, showing, for example, that across the roughly 10 million doses delivered, 1 of every 5 immunized a susceptible child. Finally, we use the model to explore a counter-factual epidemiology without the 2019–2020 campaigns, and we estimate that those interventions prevented over 10,000 deaths.

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