Research progress on N6-methyladenosine and non-coding RNA in multiple myeloma

Xiaoqi Sun; Yongming Zhou; Wenwei Zhu; Hailin Chen

doi:10.1007/s12672-025-02386-6

Discover Oncology (Apr 2025)

Research progress on N6-methyladenosine and non-coding RNA in multiple myeloma

Xiaoqi Sun,
Yongming Zhou,
Wenwei Zhu,
Hailin Chen

Affiliations

Xiaoqi Sun: Department of Hematology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Yongming Zhou: Department of Hematology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Wenwei Zhu: Department of Hematology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Hailin Chen: Department of Hematology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

DOI: https://doi.org/10.1007/s12672-025-02386-6
Journal volume & issue: Vol. 16, no. 1
pp. 1 – 12

Abstract

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Abstract N6-methyladenosine (m6A) and non-coding RNA (ncRNA) play important roles in the occurrence, development, and prognosis of multiple myeloma (MM). They not only affect stemness, growth, and apoptosis of MM cells but also intervene in MM proliferation, migration, invasion, and even drug resistance. It is also a prognostic factor for poor MM survival. Therefore, in-depth research on the mechanisms of m6A and ncRNA in MM significant for diagnosis, treatment, and prognosis of MM.

Published in Discover Oncology

ISSN: 2730-6011 (Online)
Publisher: Springer
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.springer.com/journal/12672/

About the journal

Abstract

Keywords