Translational Research in Urology (Feb 2020)
Effect of Modified Vacuum in Patients with Peyronie’s Disease and Erectile Dysfunction
Abstract
Introduction Peyronie's disease (PD) is a penile disease that is characterized by penile pain, curvature, shortening, and plaque in the penis which usually ends up in erectile dysfunction (ED). This study is to assess the efficacy of modified vacuum therapy in patients with PD and ED. The basic principle of the study is similar to modeling performed during penile implant surgery. Methods This study is performed on 43 Patients who is practiced with three different vacuum cylinders 30 minutes, 3 times a day for 3 months. First, the second, and third months with the smallest, medium, and the biggest cylinder were used respectively. Parameters were recorded before the beginning of the study at the end of each month. Assessment includes number and size of the plaque, angle of penile curvature (by erection induced with vacuum constriction device (VCD)), pain during erection, the status of morning erection, quality of an erection, and various previous treatments. There was a clinically and statistically significant improvement in the angle of curvature, size, and numbers of plaque. Results A total of 43 patients with a mean age of 56.3 years(40-74) years participated in the study. There was a significant reduction in plaque size and curvature. The mean of plaque size and curvature was 1.39cm and 31.28 degrees respectively at the presentation which was reduced to 0.64 (0-3)cm and 11.6 degrees respectively at the end of the study. At the end of the study, 30(69.7%) patients were satisfied with the outcome and wanted no further treatment. There was no major side effect observed in patients using the device. Conclusions We recommend the use of a modified vacuum device with the mentioned method for PD and ED with curvature less than 45 degrees and plaque size less than 2cm. It is safe to use in all stages of the disease and can help patients to attain erection with VCD.
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