Вопросы современной педиатрии (Jul 2010)

NEW OPPORTUNITIES IN TREATMENT OF SEVERE SYSTEMIC TYPE OF JUVENILE ARTHRITIS

  • R.V. Denisova,
  • E.I. Alexeeva,
  • A.O. Lisitsin,
  • S.I. Valieva,
  • T.M. Bzarova

Journal volume & issue
Vol. 9, no. 4
pp. 160 – 167

Abstract

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The article presents a case report of a severe clinical course of systemic type of juvenile arthritis, resistant to treatment with corticosteroids and classic immunosuppressive agents in girl 9 years old. Biological agent — tocilizumab showed beneficial effect: exudative lesions of joints, morning joint stiffness stopped and the range of motions restored in almost all affected joints in 8 weeks of treatment. A girl became more active, her emotional state improved. Laboratory signs of disease’s activity (ESR, concentration of C-reactive protein in plasma) were normalized in 4 weeks. The drug induced development of clinical and laboratory remission of a disease.Key words: children, juvenile arthritis, treatment, tocilizumab.(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(4):160-167)