Nature Communications (Jul 2019)

Single-crosslink microscopy in a biopolymer network dissects local elasticity from molecular fluctuations

  • Lingxiang Jiang,
  • Qingqiao Xie,
  • Boyce Tsang,
  • Steve Granick

DOI
https://doi.org/10.1038/s41467-019-11313-7
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 8

Abstract

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The intrinsic inhomogeneity of polymer networks is masked by the usual ensemble-averaged measurements. Here the authors construct direct maps of crosslinks in an actin network by selective labeling the crosslinks with fluorescent markers and characterize the local elasticity and cross-correlation between crosslinks.