Química Nova (Jan 2008)

Investigação do potencial antioxidante e anticolinesterásico de Hippeastrum (Amaryllidaceae) Antioxidant and anticolinesterasic effects of Hippeastrum species (Amaryllidaceae)

  • Raquel Brandt Giordani,
  • Letícia Balvedi Pagliosa,
  • Amélia T. Henriques,
  • José Angelo S. Zuanazzi,
  • Julie H. A. Dutilh

DOI
https://doi.org/10.1590/S0100-40422008000800024
Journal volume & issue
Vol. 31, no. 8
pp. 2042 – 2046

Abstract

Read online

Amaryllidaceae family is an important source of bioactive molecules and considering the taxonomic relationships, it is relevant to investigate the genus Hippeastrum. Thus, the aim of this work was to determine antioxidant and anticholinesterasic activities of Hippeastrum morelianum, Hippeastrum psittacinum and Hippeastrum santacatarina. Both antioxidant and acetylcholinesterasic activities of extracts were determinated by bioautography as 10 mg/mL and 0.1 mg/mL, respectively. The antioxidant activity of alkaloid lycorine, determinated spectrophotometrically with DPPH, indicated an IC50 value of 0.326 mM.

Keywords