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Onychomycosis: features external therapy

Vestnik Dermatologii i Venerologii. 2017;0(5):90-95 DOI 10.25208/0042-4609-2016-0-5-90-95


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Journal Title: Vestnik Dermatologii i Venerologii

ISSN: 0042-4609 (Print); 2313-6294 (Online)

Publisher: State Scientific Center of Dermatovenereology and Cosmetology

Society/Institution: Russian Society of Dermatovenereology and Cosmetology

LCC Subject Category: Medicine: Dermatology

Country of publisher: Russian Federation

Language of fulltext: Russian

Full-text formats available: PDF



D. V. Zaslavsky (St. Petersburg State Pediatric Medical University)

I. N. Chuprov (State Medical University by the name I.I. Mechnikov)

A. A. Sidikov (Leningrad Regional Center of specialized types of medical care)

M. G. Khvedelidze (St. Petersburg State Pediatric Medical University)

O. B. Tatarskaya (St. Petersburg State Pediatric Medical University)


Peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 8 weeks


Abstract | Full Text

Onychomycosis - one of the most frequent diseases with defeat of a nail bed, matrics and nail plate of a fungal origin. Frequency of an onychomycosis in Russia reaches 5% (to 15 million people), and practically every tenth visit of the dermatologist is connected with this pathology. Treatment of an onychomycosis still remains very difficult task. Application of varnishes, ointments with antimycotics and local agents on an oil basis has an essential shortcoming - insufficient receipt of a preparation to the center of pathological changes. It is supposed that for optimum therapy it is necessary to influence: first, from frontal and distal part of a nail, secondly, to apply aqueous-alcoholic solutions of a preparation which can freely get into subnail spaces with the phenomena of an onycholysis. For example, it has been shown highly efficient application of naftifina a hydrochloride under control of solution of the diamond green, showing diffusion distribution active ingredient to subnail space and on channels.