Inhibition of lysine-specific demethylase 1 (LSD1) prevented tumor growth and metastasis by downregulating PD-L1 expression in lung adenocarcinoma

• Pengxing He,
• Linna Du,
• Pan Hao,
• Han Yang,
• Yufei Ren,
• Huiqin Kang,
• Yanli Ding,
• Wen Zhao,
• Yichao Xu,
• Hongmin Liu

Affiliations

Pengxing He

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China; State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou, Henan 450001, China

Linna Du

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China

Pan Hao

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China

Han Yang

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China

Yufei Ren

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China

Huiqin Kang

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China

Yanli Ding

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China

Wen Zhao

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China

Yichao Xu

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China; State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou, Henan 450001, China; Corresponding author. Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.

Hongmin Liu

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Institute of Drug Discovery & Development, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China; State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou, Henan 450001, China; Corresponding author. State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou, Henan 450001, China.