High concentration insulin

Abstract

This communication reviews available high concentration insulins and their basic as well as clinical pharmacology. It classifies all high concentration insulins, and describes their pharmacokinetic and pharmacodynamic properties. The article discusses the utility of high concentrations insulins, lists indications for these preparations, highlights caveats for their safe use, and proposes pragmatic contraindications to their prescription.

Keywords

• U200 degludec
• U200 lispro
• U300 glargine
• U500 regular insulin
• ultralong acting insulin