Crystal structure of 4-methyl-N-{[1-(4-methylbenzoyl)piperidin-4-yl]methyl}benzamide

Abstract

In the title compound, C22H27N2O2, the piperidine ring adopts a half-chair conformation with the benzene rings inclined in a trans orientation with respect to the piperidine ring [dihedral angle between the benzene rings = 89.1 (1)°]. In the crystal, a three-centre asymmetric N—H...O/C—H...O hydrogen-bonding interaction leads to the formation of chains extending along the a-axis direction.

Keywords

• crystal structure
• benzamide
• piperdine derivatives
• biological activity
• hydrogen bonding