Blood eosinophils, fractional exhaled nitric oxide and the risk of asthma attacks in randomised controlled trials: protocol for a systemic review and control arm patient-level meta-analysis for clinical prediction modelling

• Richard Beasley,
• Ian Pavord,
• Ewout Steyerberg,
• Simon Couillard

Affiliations

Richard Beasley

Medical Research Institute of New Zealand, Wellington, New Zealand

Ian Pavord

Respiratory Medicine Unit and Oxford Respiratory NIHR Biomedical Research Centre, University of Oxford, Oxford, UK

Ewout Steyerberg

7 Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands

Simon Couillard

1 Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK