Nature Communications (Feb 2019)
High-speed mechano-active multielectrode array for investigating rapid stretch effects on cardiac tissue
Abstract
While strain is known to affect cardiac electrophysiology, experimental systems to interrogate the effect of rapid strain cycles on cardiac tissue are lacking. Here the authors introduce a multielectrode array that can induce rapid dynamic strain cycles on cardiomyocyte strands and see effects of strain amplitude but not strain rate on impulse conduction.