Endocarditis and systemic embolization from Whipple’s disease
Yu Ting He,
Katherine Peterson,
Jessica Crothers,
Jean Dejace,
Andrew J. Hale
Affiliations
Yu Ting He
University of Vermont Medical Center, Burlington, VT, United States
Katherine Peterson
University of Vermont Medical Center, Burlington, VT, United States
Jessica Crothers
University of Vermont Medical Center, Larner College of Medicine at the University of Vermont, Burlington, VT, United States
Jean Dejace
University of Vermont Medical Center, Larner College of Medicine at the University of Vermont, Burlington, VT, United States
Andrew J. Hale
University of Vermont Medical Center, Larner College of Medicine at the University of Vermont, Burlington, VT, United States; Corresponding author at: University of Vermont Medical Center, Infectious Disease Unit, 111 Colchester Avenue, Mailstop 115 SM2, Burlington, VT 05401, United States.
Whipple’s disease (WD), caused by infection with the organism Tropheryma whipplei, is a rare disease that classically presents with diarrhea, weight loss, and polyarthralgia. Less commonly, Whipple’s Disease can presentation with endocarditis or neurologic infections. The authors report a patient with Whipple’s Disease endocarditis whose initial presentation was acute lower extremity arterial occlusion, and review current literature regarding the epidemiology, diagnosis, treatment, and prognosis of Whipple’s Disease endocarditis.
