Кубанский научный медицинский вестник (Aug 2014)

INFLUENCE OF PREPARATION «MELAXEN» ON LIPID PEROXIDATION AND ANTIOXIDANT SYSTEMS AT A POISONING MERCURY AND CADMIUM

  • V. B. Brin,
  • A. K. Mittsiev,
  • K. G. Mittsiev

Journal volume & issue
no. 4
pp. 30 – 33

Abstract

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Mercury and cadmium poisoning leads to the development of a powerful oxidative stress was associated with increased concentrations of malondialdehyde and hydroperoxide. These changes combined with a decrease in catalase activity, indicating that inhibition of the action of the antioxidant defense mechanisms of the system. Application melaxen in chronic intoxication with heavy metal salts, has a pronounced antioxidant effect, which leads to a reduction of lipid peroxidation and the simultaneous increase in the activity of catalase.

Keywords