Carbapenemase-producing Klebsiella pneumoniae intra-abdominal infection successfully treated with ceftazidime/avibactam plus tigecycline
Mariana Guedes,
Raquel Duro,
Telma Fonseca,
Isabel Abreu,
Nuno Rocha-Pereira
Affiliations
Mariana Guedes
Infectious Diseases Department, Centro Hospitalar Universitário de São João Alameda Prof. Hernâni Monteiro, 4200-319, Oporto, Portugal; Corresponding author at: Infectious Diseases Department, Centro Hospitalar São João, Alameda Prof. Hernâni Monteiro, 4200-319, Oporto, Portugal.
Raquel Duro
Infectious Diseases Department, Centro Hospitalar Universitário de São João Alameda Prof. Hernâni Monteiro, 4200-319, Oporto, Portugal
Telma Fonseca
General Surgery Deparment, Centro Hospitalar Universitário de São João Alameda Prof. Hernâni Monteiro, 4200-319, Oporto, Portugal
Isabel Abreu
Infectious Diseases Department, Centro Hospitalar Universitário de São João Alameda Prof. Hernâni Monteiro, 4200-319, Oporto, Portugal
Nuno Rocha-Pereira
Infectious Diseases Department, Centro Hospitalar Universitário de São João Alameda Prof. Hernâni Monteiro, 4200-319, Oporto, Portugal
Ceftazidime/avibactam combines ceftazidime with a new beta-lactam that successfully that inhibits Amber Class A and D carbapenemases.We report a clinical case of a 61 year-old man with a carbapenemase-producing Klebsiella pneumoniae intra-abdominal infection after an elective abdominal hernia repair. The infection was successfully managed with multiple abdominal surgeries, drainage and combined antibiotic therapy with ceftazidime/avibactam plus tigecycline.
