Revista Cubana de Cardiología y Cirugía Cardiovascular (Feb 2014)

Hyperglycemia, prognosis marker of adverse events in heart attack

  • Yudit García Cairo,
  • Claudio M. González Rodríguez,
  • Félix R. Jorrín Román,
  • Francisco J. Valladares Carvajal,
  • Juan J. Navarro López,
  • Suleidy Castillo Fernández

Journal volume & issue
Vol. 19, no. 2
pp. 72 – 78

Abstract

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Introduction:Hyperglycemia on admission in patient with acute coronary syndrome is common, considered bad marker of clinical evolution and death.Objective:To value the use of admission glycemia like prognosis factor of adverse events in patient with heart attack.Method:Descriptive study and longitudinal prospective. 246 patients were included with heart attack admitted in Cienfuegoshospital and their evolution was continued during 30 days. It was determined as point of a very best cut for the mortality at admission glycemia ≥ 7,1mmol/l by means of the curve ROC and one carries out analysis logistics regression toidentify independent predictors of death.Results:The patients with glycemia ≥ 7,1mmol/l prevailed the diabetes, tachycardia,killip≥II, inferior localization, small ejectionfraction and bigger incidence of adverse events (60% versus 2%, p=0,000) as heart failure(30% versus 15%; p =0,001), malign ventricular arrhythmias (23% versus 4%; p = 0,000) and death(15% versus 3%; p = 0,001), with smaller survival regarding the patients with glycemia <7,1mmol/l(85,5% in contrast with 96,6%). Age and ejection fraction wereindependent predictors of death in the multivariate analysis.Conclusions:In patient with myocardial infarction thehyperglycemia to the entrance, with a cut point ≥7,1mmol/l, predicts a short term increment of adverse events, although it was not independent predictor of death

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