Nature Communications (Jul 2020)

SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses

  • He-wei Jiang,
  • Yang Li,
  • Hai-nan Zhang,
  • Wei Wang,
  • Xiao Yang,
  • Huan Qi,
  • Hua Li,
  • Dong Men,
  • Jie Zhou,
  • Sheng-ce Tao

DOI
https://doi.org/10.1038/s41467-020-17488-8
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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Currently very little is known about how our immune system responds to SARS-CoV-2 infection. Here the authors generate a SARS-CoV-2 proteome microarray for profiling of IgG and IgM responses to COVID-19 in patients and find significant responses to ORF9b and NSP5, as well as the S1 and N proteins.