Evaluation of Some Cytogenetic Effects of Bt.ASF.1 in Lab.mice

Abstract

This study was amid to detection the genotoxicity ffect of biocide (Bt-ASF-1) producing from Bacillus thuringiensis ( by oral nutrition ) in inhibition of the Cyclophosphoamide drug in mice (Mus musculus) . Cytogenetical tests were used to determination of the mitotic index ,micronuclei , chromosomal central association and chromosomal aberration . The results revealed the absence of toxicity and mutagenicity effects of biocide and its inhibition efficiency to prevent the toxicity and mutagenicity effects of CFA drug before feeding with biocide . Keywords : Genotoxic effects of Bt-ASF-1