Herba Polonica (Mar 2020)

Antioxidant status and hepato-protective role of Anchomanes difformis in streptozotocin-induced diabetes in male Wistar rats

  • Alabi Toyin D.,
  • Brooks Nicole L.,
  • Oguntibeju Oluwafemi O.

DOI
https://doi.org/10.2478/hepo-2020-0005
Journal volume & issue
Vol. 66, no. 1
pp. 18 – 36

Abstract

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Introduction: The liver is involved in the metabolism of xenobiotics and their metabolites and it is vulnerable to oxidative damage. Hyperglycaemia is highly implicated in the progression of diabetes mellitus, and adversely affects the liver. Though, conventional hypoglycaemic drugs may be effective in reducing blood glucose, they do not appear to be effective in attenuating the progression of diabetes and its complications.

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