Nature Communications (May 2019)

Capturing single-cell heterogeneity via data fusion improves image-based profiling

  • Mohammad H. Rohban,
  • Hamdah S. Abbasi,
  • Shantanu Singh,
  • Anne E. Carpenter

DOI
https://doi.org/10.1038/s41467-019-10154-8
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 6

Abstract

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A challenge with single-cell resolution methods is that cell heterogeneity should be captured while allowing for comparisons between populations. Here the authors fuse information from the dispersion profiles with the average profiles at the level of profiles’ similarity matrices for single cell imaging data.