Nature Communications (May 2022)

Wireless implantable optical probe for continuous monitoring of oxygen saturation in flaps and organ grafts

  • Hexia Guo,
  • Wubin Bai,
  • Wei Ouyang,
  • Yihan Liu,
  • Changsheng Wu,
  • Yameng Xu,
  • Yang Weng,
  • Hao Zang,
  • Yiming Liu,
  • Lauren Jacobson,
  • Ziying Hu,
  • Yihang Wang,
  • Hany M. Arafa,
  • Quansan Yang,
  • Di Lu,
  • Shuo Li,
  • Lin Zhang,
  • Xun Xiao,
  • Abraham Vázquez-Guardado,
  • Joanna Ciatti,
  • Elizabeth Dempsey,
  • Nayereh Ghoreishi-Haack,
  • Emily A. Waters,
  • Chad R. Haney,
  • Amanda M. Westman,
  • Matthew R. MacEwan,
  • Mitchell A. Pet,
  • John A. Rogers

DOI
https://doi.org/10.1038/s41467-022-30594-z
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

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Although continuous monitoring of tissue oxygenation is critically important after tissue/organ graft procedures, current technologies have key limitations. Here, the authors develop a miniaturized, minimally invasive, self-anchoring optical probe and demonstrate continuous monitoring of oxygenation in porcine flap and organ models.