Romanian Journal of Oral Rehabilitation (Mar 2023)

PHARMACEUTICAL FORMS USED IN DEPIGMENTATION

  • Olimpia Dumitriu Buzia,
  • Kamel Earar,
  • Mihaela Cojocaru,
  • Denisa Batir Marin,
  • Carmen Tiutiucă,
  • Sergiu Ciprian Focșăneanu,
  • Oleg Solomon,
  • Emil Ceban

Journal volume & issue
Vol. 15, no. 1
pp. 209 – 218

Abstract

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The aim of this work is to propose therapeutic formulas for the treatment of pigmentation disorders, in the context of the high incidence of this dermatological pathology The work gives a broad presentation of pigmentation disorders, starting from the structure of the skin, from melanogenesis, to the regulation of melanogenesis. The objectives of this work consisted in obtaining pharmaceutical preparations that treat or alleviate the aesthetic discomforts created by melasma, chloasma, ephelide or senile lentigo. The novelty of this study consists in the association of active substances such as tretinoin with dexamethasone and vitamin C, in order to make the two pharmaceutical forms applicable in dermatology.

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